Vitamin D is the body’s primary regulator of calcium homeostasis. It
aids with bone mineralization and skeletal development. Considered a
prohormone, vitamin D does not have hormone activity, but can be changed
into a molecule that does.
Vitamin D helps blood cell formation, immunity, and helps cells
“differentiate,” which may lower cancer risks. Vitamin D has shown in
human and animal studies to possibly provide protection from autoimmune
arthritis, multiple sclerosis, and juvenile diabetes.
Vitamin D helps the body maintain necessary insulin blood levels.
Vitamin D receptors are located in the pancreas, where insulin is
produced. Supplementation might increase the secretion of insulin in
those with type 2 diabetes.
Vitamin D has been used in those with the following health problems:
- Crohn’s Disease
- Cystic Fibrosis
- Osteoporosis
- Rickets/osteomalacia
The extent to which vitamin D can help reduce fractures and bone loss in
the elderly is still not definite, however some evidence claims that it
is useful. Vitamin C may limit or prevent perinatal growth retardation
and may alleviate some forms of psoriasis. Researchers hope to find
vitamin C to be beneficial to treat immunodulation, cancer, infertility,
and diabetes. Early research is also showing the possibility of
vitamin D being used to help seasonal depression, bilateral cochlear
deafness, increase resistance to seizures, and help with multiple
sclerosis and sick sinus syndrome.
Vitamin D Deficiency
Vitamin D deficiency in adults may cause osteomalacia, or the softening
of the bones. This condition is usually treated with calcium
supplements and vitamin D. Treatment for osteomalacia should be
diagnosed and treated by a physician. Abnormal bone formation occurs in
those with vitamin D deficiency. The deficiency is more common in the
winter when access to sunlight is restricted. Deficiencies are also
more common in highly polluted areas where ultraviolet rays from the sun
can be blocked.
Strict vegetarians, alcoholics, those with kidney or liver disease, and
dark-skinned people are more likely suffer from vitamin D deficiency.
Those with kidney or liver disease do produce vitamin D but do not
activate it.
People with intestinal malabsorption more commonly are vitamin D
deficient. Those with insufficient pancreatic function such as cystic
fibrosis or pancreatitis, or with hyperthyroidism such as Graves’
disease, are often vitamin D deficient.
Recommended Dosage
Vitamin D in supplement form can be obtained as vitamin D2
(ergocalciferol) or as vitamin D3 (cholecalciferol). Multivitamins
generally contain vitamin D. Recommended dosage is 200-400 IU, or 5-10
micrograms, each day. 400 IU are found in multi-mineral, pre- and
postnatal vitamins.
The elderly and those with malabsorption syndromes, hepatic failure, and
nephritic syndrome receive supplements with 50,000 IU, or 1,250
micrograms, weekly for an eight week period. This should only be done
under the supervision of a physician. |
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